Issue 4, 2017

Programmed dissociation of dimer and trimer origami structures by aptamer–ligand complexes

Abstract

Dimer- and trimer-origami frames are bridged by duplexes that include caged, sequence-specific, anti-ATP and/or anti-cocaine aptamer sequences. The programmed dissociation of the origami dimers or trimers in the presence of ATP and/or cocaine ligands is demonstrated. The processes are followed by AFM imaging and by electrophoretic experiments.

Graphical abstract: Programmed dissociation of dimer and trimer origami structures by aptamer–ligand complexes

Supplementary files

Article information

Article type
Communication
Submitted
19 Oct 2016
Accepted
16 Dec 2016
First published
19 Dec 2016

Nanoscale, 2017,9, 1416-1422

Programmed dissociation of dimer and trimer origami structures by aptamer–ligand complexes

N. Wu and I. Willner, Nanoscale, 2017, 9, 1416 DOI: 10.1039/C6NR08209B

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