Issue 5, 2017

Turn-on fluorescence detection of pyrophosphate anion based on DNA-attached cobalt oxyhydroxide

Abstract

The turn-on fluorescence of pyrophosphate anion (PPi) was detected using DNA-attached cobalt oxyhydroxide. The fluorescence signal was quenched when carboxyfluorescein-labeled ssDNA was adsorbed by CoOOH nanoflakes through electrostatic interaction. With the addition of target PPi, PPi competed with DNA for CoOOH nanoflakes, resulting in turn-on fluorescence.

Graphical abstract: Turn-on fluorescence detection of pyrophosphate anion based on DNA-attached cobalt oxyhydroxide

Supplementary files

Article information

Article type
Paper
Submitted
08 Nov 2016
Accepted
20 Jan 2017
First published
23 Jan 2017

New J. Chem., 2017,41, 1993-1996

Turn-on fluorescence detection of pyrophosphate anion based on DNA-attached cobalt oxyhydroxide

N. Li, Y. D. Zhu, T. Liu, S. G. Liu, S. M. Lin, Y. Shi, H. Q. Luo and N. B. Li, New J. Chem., 2017, 41, 1993 DOI: 10.1039/C6NJ03491H

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