Issue 3, 2017
From the journal:

New Journal of Chemistry

A new ESIPT-based fluorescent probe for highly selective and sensitive detection of hydrogen sulfide and its application in live-cell imaging†

Bo Chen,a   Jing Huang,a   Huiqing Geng,a   Lingli Xuan,a   Tengfei Xu,a   Xin Lib  and  Yifeng Han ORCID logo *a  

* Corresponding authors

a Department of Chemistry, The Key Laboratory of Advanced Textile Materials and Manufacturing Technology, Zhejiang Sci-Tech University, Hangzhou, China
E-mail: zstuchem@gmail.com
Tel: +86-751-86843550

b ZJU-ENS Joint Laboratory of Medicinal Chemistry, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
E-mail: lixin81@zju.edu.cn
Tel: +86-751-88981051

Abstract

A new excited-state intramolecular proton transfer (ESIPT) based fluorescent probe for the detection of hydrogen sulfide has been reasonably designed and developed. The probe operates by H2S-mediated reduction of hydroxylamine to amine and exhibits high selectivity and sensitivity under mild conditions. Furthermore, the probe was successfully used for fluorescence imaging of H2S in living cells.

Graphical abstract: A new ESIPT-based fluorescent probe for highly selective and sensitive detection of hydrogen sulfide and its application in live-cell imaging

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Article information

DOI
https://doi.org/10.1039/C6NJ03355E
Article type
Paper
Submitted
26 Oct 2016
Accepted
21 Dec 2016
First published
21 Dec 2016

New J. Chem., 2017,41, 1119-1123

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A new ESIPT-based fluorescent probe for highly selective and sensitive detection of hydrogen sulfide and its application in live-cell imaging

B. Chen, J. Huang, H. Geng, L. Xuan, T. Xu, X. Li and Y. Han, New J. Chem., 2017, 41, 1119 DOI: 10.1039/C6NJ03355E

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