Issue 6, 2017

Biocompatible conjugated polymer nanoparticles for highly efficient photoacoustic imaging of orthotopic brain tumors in the second near-infrared window

Abstract

A new second near-infrared (NIR II) conjugated polymer (CP) was designed and synthesized. The CP nanoparticles have good biocompatibility, excellent photostability and high imaging contrast, and have been successfully used to demonstrate the first example of NIR II photoacoustic imaging of orthotopic brain tumors. In comparison with existing contrast agents for photoacoustic imaging, the NIR II CP nanoparticles showed more efficient skull penetration and a much higher signal/background ratio using a 1064 nm laser.

Graphical abstract: Biocompatible conjugated polymer nanoparticles for highly efficient photoacoustic imaging of orthotopic brain tumors in the second near-infrared window

Supplementary files

Article information

Article type
Communication
Submitted
24 Aug 2017
Accepted
26 Sep 2017
First published
26 Sep 2017

Mater. Horiz., 2017,4, 1151-1156

Biocompatible conjugated polymer nanoparticles for highly efficient photoacoustic imaging of orthotopic brain tumors in the second near-infrared window

B. Guo, Z. Sheng, Kenry, D. Hu, X. Lin, S. Xu, C. Liu, H. Zheng and B. Liu, Mater. Horiz., 2017, 4, 1151 DOI: 10.1039/C7MH00672A

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