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Issue 10, 2017
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Biocatalysis engineering: the big picture

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In this tutorial review we describe a holistic approach to the invention, development and optimisation of biotransformations utilising isolated enzymes. Increasing attention to applied biocatalysis is motivated by its numerous economic and environmental benefits. Biocatalysis engineering concerns the development of enzymatic systems as a whole, which entails engineering its different components: substrate engineering, medium engineering, protein (enzyme) engineering, biocatalyst (formulation) engineering, biocatalytic cascade engineering and reactor engineering.

Graphical abstract: Biocatalysis engineering: the big picture

  • This article is part of the themed collection: Primer
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The article was received on 28 Nov 2016 and first published on 13 Mar 2017

Article type: Tutorial Review
DOI: 10.1039/C6CS00854B
Citation: Chem. Soc. Rev., 2017,46, 2678-2691

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    Biocatalysis engineering: the big picture

    R. A. Sheldon and P. C. Pereira, Chem. Soc. Rev., 2017, 46, 2678
    DOI: 10.1039/C6CS00854B

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