Issue 1, 2017
From the journal:

CrystEngComm

Solid form and solubility

Christopher A. Hunter ORCID logo *a  and  Rafel Prohensb  

* Corresponding authors

a Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK
E-mail: herchelsmith.orgchem@ch.cam.ac.uk

b Unitat de Polimorfisme i Calorimetria, Centres Científics i Tecnològics, Universitat de Barcelona, Baldiri Reixac 10, 08028 Barcelona, Spain

Abstract

Factors that determine the solubility of polymorphs and cocrystals are analysed using experimental data to show that the change in the solubility of a compound produced by the formation of a multicomponent crystal can be estimated in a straightforward manner, if the solubilities of the pure compound and the coformer are known.

Graphical abstract: Solid form and solubility

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Article information

DOI
https://doi.org/10.1039/C6CE02094A
Article type
Communication
Submitted
28 Sep 2016
Accepted
29 Nov 2016
First published
08 Dec 2016

CrystEngComm, 2017,19, 23-26

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Solid form and solubility

C. A. Hunter and R. Prohens, CrystEngComm, 2017, 19, 23 DOI: 10.1039/C6CE02094A

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