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Issue 96, 2017
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Biofilm dispersal using nitric oxide loaded nanoparticles fabricated by photo-PISA: influence of morphology

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Abstract

Polymeric nanoparticles (NPs) of different morphologies (spheres and worms) were synthesized using a visible light mediated polymerization-induced self-assembly (PISA) approach. Spherical and worm-like NPs were subsequently modified to generate diazeniumdiolate functionalized NPs. Interestingly, the NO release rate and the dispersal of biofilms were found to strongly depend on the NP morphology. NPs with a higher aspect ratio (worms) exhibited a slower NO release rate and greater biofilm dispersal after 1 h of incubation.

Graphical abstract: Biofilm dispersal using nitric oxide loaded nanoparticles fabricated by photo-PISA: influence of morphology

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Supplementary files

Article information


Submitted
18 Sep 2017
Accepted
15 Nov 2017
First published
21 Nov 2017

Chem. Commun., 2017,53, 12894-12897
Article type
Communication

Biofilm dispersal using nitric oxide loaded nanoparticles fabricated by photo-PISA: influence of morphology

Z. Sadrearhami, J. Yeow, T. Nguyen, K. K. K. Ho, N. Kumar and C. Boyer, Chem. Commun., 2017, 53, 12894
DOI: 10.1039/C7CC07293G

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