Issue 72, 2017
From the journal:

Chemical Communications

A cancer cell specific targeting nanocomplex for combination of mRNA-responsive photodynamic and chemo-therapy†

Xiaolong Zhang, ORCID logo ab   Xionghong Tan,c   Da Zhang,ab   Naishun Liao,ab   Youshi Zheng,ab   Aixian Zheng,ab   Yongyi Zeng,abd   Xiaolong Liu ORCID logo *ab  and  Jingfeng Liu*abd  

* Corresponding authors

a The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P. R. China
E-mail: xiaoloong.liu@gmail.com, drjingfeng@126.com

b The Liver Center of Fujian Province, Fujian Medical University, Fuzhou 350025, P. R. China

c Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, P. R. China

d Liver Disease Center, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, P. R. China

Abstract

We have developed a cancer cell specific targeting nanocomplex which combines photodynamic therapy with chemotherapy through precisely responding to the intracellular tumor-related mRNA. The combined treatment of these two modalities showed significantly enhanced therapeutic effects on cancer cells.

Graphical abstract: A cancer cell specific targeting nanocomplex for combination of mRNA-responsive photodynamic and chemo-therapy

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Article information

DOI
https://doi.org/10.1039/C7CC05295B
Article type
Communication
Submitted
09 Jul 2017
Accepted
16 Aug 2017
First published
16 Aug 2017

Chem. Commun., 2017,53, 9979-9982

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A cancer cell specific targeting nanocomplex for combination of mRNA-responsive photodynamic and chemo-therapy

X. Zhang, X. Tan, D. Zhang, N. Liao, Y. Zheng, A. Zheng, Y. Zeng, X. Liu and J. Liu, Chem. Commun., 2017, 53, 9979 DOI: 10.1039/C7CC05295B

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