Issue 69, 2017
From the journal:

Chemical Communications

In situ generation of electrochemiluminescent DNA nanoflowers as a signal tag for mucin 1 detection based on a strategy of target and mimic target synchronous cycling amplification†

Sheng-Kai Li,a   An-Yi Chen,a   Xiao-Xue Niu,a   Zhi-Ting Liu,a   Min Du,a   Ya-Qin Chai,a   Ruo Yuan ORCID logo *a  and  Ying Zhuo ORCID logo *a  

* Corresponding authors

a Key Laboratory of Luminescence and Real-Time Analytical Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China
E-mail: yuanruo@swu.edu.cn, yingzhuo@swu.edu.cn
Fax: +86-23-68253172
Tel: +86-23-68252277

Abstract

A sensitive electrochemiluminescent (ECL) aptasensor consisting of a novel ECL signal tag of DNA nanoflowers (DNA NFs) and a highly efficient target conversion strategy for the MUC1 assay was developed, which not only increased the stability for luminophore loading, but also greatly improved the detection sensitivity.

Graphical abstract: In situ generation of electrochemiluminescent DNA nanoflowers as a signal tag for mucin 1 detection based on a strategy of target and mimic target synchronous cycling amplification

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Article information

DOI
https://doi.org/10.1039/C7CC04747A
Article type
Communication
Submitted
19 Jun 2017
Accepted
04 Aug 2017
First published
08 Aug 2017

Chem. Commun., 2017,53, 9624-9627

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In situ generation of electrochemiluminescent DNA nanoflowers as a signal tag for mucin 1 detection based on a strategy of target and mimic target synchronous cycling amplification

S. Li, A. Chen, X. Niu, Z. Liu, M. Du, Y. Chai, R. Yuan and Y. Zhuo, Chem. Commun., 2017, 53, 9624 DOI: 10.1039/C7CC04747A

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