Jump to main content
Jump to site search

Issue 69, 2017
Previous Article Next Article

Discovery of synthetic small molecules that enhance the number of stomata: C–H functionalization chemistry for plant biology

Author affiliations

Abstract

The increasing climate changes and global warming are leading to colossal agricultural problems such as abatement of food production and quality. As stomatal development is considered to play a key role in crop plant productivity and water-use efficiency, studying stomatal development is useful for understanding the productivity of plant systems for both natural and agricultural systems. Herein, we report the first-in-class synthetic small molecules enhancing the number of stomata in Arabidopsis thaliana that have been discovered by screening of the chemical library and further optimized by the Pd-catalyzed C–H arylation reaction. The present study shows not only huge potential of small molecules to control the cellular and developmental processes of stomata without using genetically modified plants, but also the power of C–H functionalization chemistry to rapidly identify the optimized compounds.

Graphical abstract: Discovery of synthetic small molecules that enhance the number of stomata: C–H functionalization chemistry for plant biology

Back to tab navigation

Supplementary files

Publication details

The article was received on 11 Jun 2017, accepted on 07 Aug 2017 and first published on 15 Aug 2017


Article type: Communication
DOI: 10.1039/C7CC04526C
Citation: Chem. Commun., 2017,53, 9632-9635
  •   Request permissions

    Discovery of synthetic small molecules that enhance the number of stomata: C–H functionalization chemistry for plant biology

    A. Ziadi, N. Uchida, H. Kato, R. Hisamatsu, A. Sato, S. Hagihara, K. Itami and K. U. Torii, Chem. Commun., 2017, 53, 9632
    DOI: 10.1039/C7CC04526C

Search articles by author

Spotlight

Advertisements