Modified biovectors for the tuneable activation of anti-platelet carbon monoxide release

Lucas Prieto; Jeremie Rossier; Katarzyna Derszniak; Jakub Dybas; René M. Oetterli; Emmanuel Kottelat; Stefan Chlopicki; Felix Zelder; Fabio Zobi

doi:10.1039/C7CC03642F

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Modified biovectors for the tuneable activation of anti-platelet carbon monoxide release†

Lucas Prieto,^a Jeremie Rossier,^c Katarzyna Derszniak,^b Jakub Dybas,^b René M. Oetterli,^a Emmanuel Kottelat,^c Stefan Chlopicki,*^bd Felix Zelder

*^a and Fabio Zobi

*^c

Author affiliations

* Corresponding authors

^a University of Zurich, Department of Chemistry, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland
E-mail: felix.zelder@chem.uzh.ch
Web: www.felix-zelder.net
Fax: +41 44 635 6803

^b Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland

^c Department of Chemistry, University of Fribourg, Chemin du Musée 9, 1700 Fribourg, Switzerland
E-mail: fabio.zobi@unifr.ch

^d Chair of Pharmacology, Jagiellonian University Medical College, Krakow, Poland
E-mail: stefan.chlopicki@jcet.eu

Abstract

This communication describes the anti-platelet effects of a new class of cis-rhenium(II)-dicarbonyl-vitamin B₁₂ complexes (B₁₂-ReCORMs) with tuneable CO releasing properties.

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Article information

DOI: https://doi.org/10.1039/C7CC03642F
Article type: Communication
Submitted: 10 May 2017
Accepted: 01 Jun 2017
First published: 01 Jun 2017

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Chem. Commun., 2017,53, 6840-6843

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Modified biovectors for the tuneable activation of anti-platelet carbon monoxide release

L. Prieto, J. Rossier, K. Derszniak, J. Dybas, R. M. Oetterli, E. Kottelat, S. Chlopicki, F. Zelder and F. Zobi, Chem. Commun., 2017, 53, 6840 DOI: 10.1039/C7CC03642F

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Chemical Communications

Modified biovectors for the tuneable activation of anti-platelet carbon monoxide release†

Abstract

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Modified biovectors for the tuneable activation of anti-platelet carbon monoxide release

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