Issue 42, 2017
From the journal:

Chemical Communications

A programmed terminal extension strategy to light up multiple beacons for DNA and cellular telomerase detection†

Yucai Yang,a   Chao Li,b   Xiaolu Hu,b   Yi Yang,b   Yongmei Yin*a  and  Zhaoxia Wang ORCID logo *c  

* Corresponding authors

a Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, P. R. China
E-mail: ym.yin@hotmail.com

b State Key Laboratory of Pharmaceutical Biotechnology, Department of Biochemistry, Nanjing University, Nanjing 210093, P. R. China

c Department of Oncology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing 210011, P. R. China
E-mail: wangzhaoxia@njmu.edu.cn

Abstract

Here we develop a new method for the sensitive detection of DNA and cellular telomerase using an enzyme-triggered terminal extension strategy that the produced strand can light up multiple beacons on the surface of gold nanoparticles.

Graphical abstract: A programmed terminal extension strategy to light up multiple beacons for DNA and cellular telomerase detection

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C7CC02515G
Article type
Communication
Submitted
01 Apr 2017
Accepted
04 May 2017
First published
04 May 2017

Chem. Commun., 2017,53, 5752-5755

Permissions

Request permissions

A programmed terminal extension strategy to light up multiple beacons for DNA and cellular telomerase detection

Y. Yang, C. Li, X. Hu, Y. Yang, Y. Yin and Z. Wang, Chem. Commun., 2017, 53, 5752 DOI: 10.1039/C7CC02515G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements