Issue 25, 2017
From the journal:

Chemical Communications

NO-Responsive vesicles as a drug delivery system†

Zhi-Heng Li, ORCID logo a   Zheng-Li Tan, ORCID logo a   Ai-Xiang Ding,a   Bing Gong,ab   Zhong-Lin Lu ORCID logo *a  and  Lan He*c  

* Corresponding authors

a Key Laboratory of Theoretical and Computational Photochemistry, Ministry of Education, College of Chemistry, Beijing Normal University, Xinjiekouwai Street 19, Beijing 100875, China
E-mail: luzl@bnu.edu.cn

b Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY 14260, USA

c National Institute for Food and Drug Control, Institute of Chemical Drug Control, TianTanXiLi 2, Beijing, China
E-mail: helan1961@aliyun.com

Abstract

A rationally designed amphiphile containing a hydrophobic Hantzsch ester and a hydrophilic phosphate ester was able to form vesicles in aqueous solution, and resulted in the first example of a NO-responsive drug delivery system.

Graphical abstract: NO-Responsive vesicles as a drug delivery system

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Article information

DOI
https://doi.org/10.1039/C7CC00918F
Article type
Communication
Submitted
04 Feb 2017
Accepted
03 Mar 2017
First published
03 Mar 2017

Chem. Commun., 2017,53, 3535-3538

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NO-Responsive vesicles as a drug delivery system

Z. Li, Z. Tan, A. Ding, B. Gong, Z. Lu and L. He, Chem. Commun., 2017, 53, 3535 DOI: 10.1039/C7CC00918F

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