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Preorientation of the terminal coumarins of a crown ether with the assistance of taco-type host–guest complex formation promotes regio- and stereo-selectivity of coumarin photodimerization to give only the syn head-to-tail coumarin isomer.

Graphical abstract: Taco complex-templated highly regio- and stereo-selective photodimerization of a coumarin-containing crown ether

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