Issue 17, 2017

Emergence through delicate balance between the steric factor and molecular orientation: a highly bright and photostable DNA marker for real-time monitoring of cell growth dynamics

Abstract

Due to its remarkable structural and optical stability in biological milieu, a newly developed small molecule based DNA marker with high brightness (Φ = 0.51, brightness = 26 300 M−1 cm−1) and almost zero toxicity has been explored. For the first time to our knowledge, this approach has provided real-time monitoring of growth and reproductive potency of living cells beyond nine days.

Graphical abstract: Emergence through delicate balance between the steric factor and molecular orientation: a highly bright and photostable DNA marker for real-time monitoring of cell growth dynamics

Supplementary files

Article information

Article type
Communication
Submitted
23 Nov 2016
Accepted
24 Jan 2017
First published
24 Jan 2017

Chem. Commun., 2017,53, 2571-2574

Emergence through delicate balance between the steric factor and molecular orientation: a highly bright and photostable DNA marker for real-time monitoring of cell growth dynamics

P. Gaur, A. Kumar, R. Dalal, S. Bhattacharyya and S. Ghosh, Chem. Commun., 2017, 53, 2571 DOI: 10.1039/C6CC09355H

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