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Issue 8, 2017
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Bioconjugation strategies to couple supramolecular exo-functionalized palladium cages to peptides for biomedical applications

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Abstract

Supramolecular Pd2L4 cages (L = ligand) hold promise as drug delivery systems. With the idea of achieving targeted delivery of the metallacages to tumor cells, the bioconjugation of exo-functionalized self-assembled Pd2L4 cages to peptides following two different approaches is reported for the first time. The obtained bioconjugates were analyzed and identified by high-resolution mass spectrometry.

Graphical abstract: Bioconjugation strategies to couple supramolecular exo-functionalized palladium cages to peptides for biomedical applications

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Article information


Submitted
09 Nov 2016
Accepted
03 Jan 2017
First published
05 Jan 2017

Chem. Commun., 2017,53, 1405-1408
Article type
Communication

Bioconjugation strategies to couple supramolecular exo-functionalized palladium cages to peptides for biomedical applications

J. Han, A. Schmidt, T. Zhang, H. Permentier, G. M. M. Groothuis, R. Bischoff, F. E. Kühn, P. Horvatovich and A. Casini, Chem. Commun., 2017, 53, 1405
DOI: 10.1039/C6CC08937B

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