Issue 13, 2017
From the journal:

Analyst

Assessment of nanoparticles’ safety: corrected absorbance-based toxicity test†

Debora Bonvin, ORCID logo a   Heinrich Hofmanna  and  Marijana Mionić Ebersold ORCID logo *abc  

* Corresponding authors

a Powder Technology Laboratory, Institute of Materials, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

b Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL), Switzerland
E-mail: Marijana.Mionic-Ebersold@chuv.ch

c Center of Biomedical Imaging (CIBM), Lausanne, Switzerland

Abstract

We developed a method to correct absorbance-based toxicity tests to remove the influence of the deposited dose of nanoparticles. As a model of absorbance-based toxicity tests, we chose the frequently used MTS test. The corrected cell viabilities obtained with the MTS test matched the results of the fluorescence-based PrestoBlue® test.

Graphical abstract: Assessment of nanoparticles’ safety: corrected absorbance-based toxicity test

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C7AN00382J
Article type
Communication
Submitted
04 Mar 2017
Accepted
24 May 2017
First published
24 May 2017

Analyst, 2017,142, 2338-2342

Permissions

Request permissions

Assessment of nanoparticles’ safety: corrected absorbance-based toxicity test

D. Bonvin, H. Hofmann and M. Mionić Ebersold, Analyst, 2017, 142, 2338 DOI: 10.1039/C7AN00382J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements