A signal-accumulating DNAzyme-crosslinked hydrogel for colorimetric sensing of hydrogen peroxide

Abstract

A signal-accumulating DNAzyme-crosslinked hydrogel was designed and prepared for colorimetric sensing of hydrogen peroxide. In this hydrogel-based sensing system, sensing signal molecules were effectively accumulated inside the gel and the concentrated DNAzyme inside the gel remarkably increased the catalytic activity, resulting in a rapid and highly sensitive detection of hydrogen peroxide.