Electrochemical behavior of surgical 316L stainless steel eye glaucoma shunt (Ex-PRESS) in artificial aqueous humor

Abstract

A novel system of electrodeposited gold nanoparticles on a carbon paste electrode was utilized as an electrochemical sensor to monitor the corrosion performance of 316L stainless steel alloy in aqueous humor containing moxifloxacin hydrochloride (MFH) drug. Electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV) and potentiodynamic polarization measurements were used to estimate the corrosion performance of 316L stainless steel alloy in aqueous humor with immersion time. The experimental data was confirmed by scanning electron microscopy (SEM), Energy dispersive X-ray analysis (EDX) and antibacterial activity. All techniques conform well to each other and confirmed that the tested alloy corrosion decreases with increasing immersion time in aqueous humor. Corrosion is more inhibited after the addition of MFH drug. In addition, as the concentration of the drug increases, the protection efficiency of the tested alloy increases. This behavior was confirmed by sensing the drug concentration with time using the modified carbon paste electrode.