Mesoporous silicon nanoparticles for targeted two-photon theranostics of prostate cancer

Arnaud Chaix; Khaled El Cheikh; Elise Bouffard; Marie Maynadier; Dina Aggad; Vanja Stojanovic; Nikola Knezevic; Marcel Garcia; Philippe Maillard; Alain Morère; Magali Gary-Bobo; Laurence Raehm; Sébastien Richeter; Jean-Olivier Durand; Frédérique Cunin

doi:10.1039/C6TB00690F

Mesoporous silicon nanoparticles for targeted two-photon theranostics of prostate cancer†

Arnaud Chaix,^a Khaled El Cheikh,^b Elise Bouffard,^b Marie Maynadier,^c Dina Aggad,^b Vanja Stojanovic,^b Nikola Knezevic,^a Marcel Garcia,^b Philippe Maillard,^d Alain Morère,^b Magali Gary-Bobo,*^b Laurence Raehm,^a Sébastien Richeter,^a Jean-Olivier Durand*^a and Frédérique Cunin*^a

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^a Institut Charles Gerhardt Montpellier, UMR 5253 CNRS-ENSCM-UM, Ecole Nationale Supérieure de Chimie Montpellier, 8 rue de l'Ecole Normale, 34296 Montpellier, France
E-mail: frédérique.cunin@enscm.fr, durand@univ-montp2.fr

^b Institut des Biomolécules Max Moussseron, UMR 5247 CNRS-UM, 15 Avenue Charles Flahault, BP 14491, 34093 Montpellier Cedex 05, France
E-mail: magali.gary-bobo@univ-montp1.fr

^c NanoMedSyn, 15 Avenue Charles Flahault, 34093 Montpellier Cedex, France

^d Institut Curie-Recherche, UMR 176, Bât 112, Centre Universitaire, Orsay, France

Abstract

A novel non-toxic porous silicon nanoparticle grafted with a mannose-6-phosphate analogue and applicable in 2-photon imaging and photodynamic therapy was specifically designed for targeting prostate cancer cells.

Journal of Materials Chemistry B

Mesoporous silicon nanoparticles for targeted two-photon theranostics of prostate cancer†

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Mesoporous silicon nanoparticles for targeted two-photon theranostics of prostate cancer

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