Jump to main content
Jump to site search

Issue 9, 2016
Previous Article Next Article

Enzymatically activated emulsions stabilised by interfacial nanofibre networks

Author affiliations

Abstract

We report on-demand formation of emulsions stabilised by interfacial nanoscale networks. These are formed through biocatalytic dephosphorylation and self-assembly of Fmoc(9-fluorenylmethoxycarbonyl)dipeptide amphiphiles in aqueous/organic mixtures. This is achieved by using alkaline phosphatase which transforms surfactant-like phosphorylated precursors into self-assembling aromatic peptide amphiphiles (Fmoc-tyrosine-leucine, Fmoc-YL) that form nanofibrous networks. In biphasic organic/aqueous systems, these networks form preferentially at the interface thus providing a means of emulsion stabilisation. We demonstrate on-demand emulsification by enzyme addition, even after storage of the biphasic mixture for several weeks. Experimental (Fluorescence, FTIR spectroscopy, fluorescence microscopy, electron microscopy, atomic force microscopy) and computational techniques (atomistic molecular dynamics) are used to characterise the interfacial self-assembly process.

Graphical abstract: Enzymatically activated emulsions stabilised by interfacial nanofibre networks

Back to tab navigation

Supplementary files

Article information


Submitted
05 Nov 2015
Accepted
22 Jan 2016
First published
22 Jan 2016

Soft Matter, 2016,12, 2623-2631
Article type
Paper

Enzymatically activated emulsions stabilised by interfacial nanofibre networks

I. P. Moreira, I. R. Sasselli, D. A. Cannon, M. Hughes, D. A. Lamprou, T. Tuttle and R. V. Ulijn, Soft Matter, 2016, 12, 2623 DOI: 10.1039/C5SM02730F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements