Issue 8, 2016

Readily accessible multifunctional fluorous emulsions


Strategies for the facile fabrication of nanoscale materials and devices represent an increasingly important challenge for chemists. Here, we report a simple, one-pot procedure for the formation of perfluorocarbon emulsions with defined functionalization. The fluorous core allows for small molecules containing a fluorous tail to be stabilized inside the emulsions. The emulsions can be formed using a variety of hydrophilic polymers resulting in an array of sizes (90 nm to >1 micron) and surface charges (−95 mV to 65 mV) of fluid particles. The surface of the emulsions can be further functionalized, covalently or non-covalently, through in situ or post-emulsion modification. The total preparation time is 30 minutes or less from commercially available reagents without specialized equipment. We envision these emulsions to be applicable to both biological and materials systems.

Graphical abstract: Readily accessible multifunctional fluorous emulsions

Supplementary files

Article information

Article type
Edge Article
23 Jan 2016
17 Apr 2016
First published
26 Apr 2016
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2016,7, 5091-5097

Readily accessible multifunctional fluorous emulsions

E. M. Sletten and T. M. Swager, Chem. Sci., 2016, 7, 5091 DOI: 10.1039/C6SC00341A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity