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Issue 2, 2016
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Pot economy and one-pot synthesis

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The one-pot synthesis of a target molecule in the same reaction vessel is widely considered to be an efficient approach in synthetic organic chemistry. In this review, the characteristics and limitations of various one-pot syntheses of biologically active molecules are explained, primarily involving organocatalytic methods as key tactics. Besides catalysis, the pot-economy concepts presented herein are also applicable to organometallic and organic reaction methods in general.

Graphical abstract: Pot economy and one-pot synthesis

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Article information

07 Aug 2015
26 Nov 2015
First published
06 Jan 2016

This article is Open Access
All publication charges for this article have been paid for by the Royal Society of Chemistry

Chem. Sci., 2016,7, 866-880
Article type

Pot economy and one-pot synthesis

Y. Hayashi, Chem. Sci., 2016, 7, 866 DOI: 10.1039/C5SC02913A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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