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Issue 109, 2016, Issue in Progress
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Solubility study of tobramycin in room temperature ionic liquids: an experimental and computational based study

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Abstract

Herein, we present a computational and experimental study assessing the solubility of tobramycin 1 in a series of hydrophilic room temperature ionic liquids (RTIL). We show that hydrophilic ionic liquids, in particular those containing acetate, [OAc], enable significantly enhanced solubilisation of tobramycin in comparison to conventional molecular solvents.

Graphical abstract: Solubility study of tobramycin in room temperature ionic liquids: an experimental and computational based study

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Article information


Submitted
15 Sep 2016
Accepted
03 Nov 2016
First published
04 Nov 2016

RSC Adv., 2016,6, 107214-107218
Article type
Communication

Solubility study of tobramycin in room temperature ionic liquids: an experimental and computational based study

R. Cunningham, N. C. Forero-Martinez, C. Hardacre, T. G. A. Youngs and M. E. Migaud, RSC Adv., 2016, 6, 107214
DOI: 10.1039/C6RA23078D

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