Control of the release of functional payloads from redox-responsive nanocapsules

Abstract

Stimuli-responsive nanocontainers allow for storage and controlled release of functional payloads in response to external stimuli. However, release profiles in which no leakage occurs without stimuli and complete release is achieved upon activation, are still a challenge. Herein, we conducted a systematic study of the factors contributing to the final release profiles of payloads from nanocapsules that are the diffusion of payloads due to the porosity of the shell and the release of payloads after activation with an external stimulus. This study provides fundamental information for designing nanocarriers that are able to effectively encapsulate and control release of payloads in response to the change in their surrounding environment.