Issue 94, 2016
From the journal:

RSC Advances

A novel combined method of thin-film evaporation and a supercritical carbon dioxide technique to prepare a fluorescent siRNA-liposome†

Lielie Lia  and  Xueqin An*a  

* Corresponding authors

a School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai, China
E-mail: anxueqin@ecust.edu.cn
Fax: +86 021 64250804

Abstract

A novel folate-DTX/siRNA-liposome (FDSL) was prepared by a combined method of thin-film evaporation and supercritical carbon dioxide technique. The FDSLs not only have good stability, lower solvent residue, high encapsulation efficiency and fluorescent tracing ability, but also possess distinct selectivity to accumulate in Bcap-37 breast cancer cells.

Graphical abstract: A novel combined method of thin-film evaporation and a supercritical carbon dioxide technique to prepare a fluorescent siRNA-liposome

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Article information

DOI
https://doi.org/10.1039/C6RA19751E
Article type
Communication
Submitted
04 Aug 2016
Accepted
01 Sep 2016
First published
20 Sep 2016

RSC Adv., 2016,6, 92115-92119

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A novel combined method of thin-film evaporation and a supercritical carbon dioxide technique to prepare a fluorescent siRNA-liposome

L. Li and X. An, RSC Adv., 2016, 6, 92115 DOI: 10.1039/C6RA19751E

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