Rapid and selective detection of cysteine over homocysteine and glutathione by a simple and effective coumarin-based fluorescent probe

Yan-Fei Kang; Hai-Xia Qiao; Ya-Li Meng; Sai-Jin Cui; Ya-Jun Han; Zhi-Yong Wu; Jie Wu; Xiao-Hui Jia; Xiao-Lei Zhang; Ming-Yan Dai

doi:10.1039/C6RA19267J

Rapid and selective detection of cysteine over homocysteine and glutathione by a simple and effective coumarin-based fluorescent probe†

Yan-Fei Kang,‡*^a Hai-Xia Qiao,‡^a Ya-Li Meng,‡^a Sai-Jin Cui,^a Ya-Jun Han,^a Zhi-Yong Wu,^b Jie Wu,^a Xiao-Hui Jia,^a Xiao-Lei Zhang^a and Ming-Yan Dai^a

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* Corresponding authors

^a College of Laboratory Medicine, Hebei North University, Zhangjiakou, China
E-mail: kangyanfei172@163.com
Fax: +86-313-4029275
Tel: +86-18931319293

^b College of Science, Hebei North University, Zhangjiakou, China

Abstract

A fluorescent probe, with coumarin as the fluorophore, is capable of detecting cysteine over other biothiols, such as homocysteine and glutathione.

RSC Advances

Rapid and selective detection of cysteine over homocysteine and glutathione by a simple and effective coumarin-based fluorescent probe†

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Rapid and selective detection of cysteine over homocysteine and glutathione by a simple and effective coumarin-based fluorescent probe

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