Issue 86, 2016, Issue in Progress

Electrochemical evidence for inclusion complexes of thiotriazinone with cyclodextrins

Abstract

The formation of the inclusion complexes of thiotriazinone (TTZ) with α-cyclodextrin and β-cyclodextrin was studied by cyclic voltammetry and 1H-NMR. The oxidation and reduction reactions specific to thiotriazinone compounds are irreversible, diffusion controlled processes, and occur in a complex mechanism. The stable inclusion of thiotriazinone in β-cyclodextrin is proved by the significant changes of redox activity characteristic for TTZ and good electrochemical stability of the complex. Moreover, the present study demonstrates that β-cyclodextrin can serve as a carrier system, since the TTZ molecule can be gradually released from the inclusion complex with time.

Graphical abstract: Electrochemical evidence for inclusion complexes of thiotriazinone with cyclodextrins

Article information

Article type
Paper
Submitted
24 Jun 2016
Accepted
15 Aug 2016
First published
15 Aug 2016

RSC Adv., 2016,6, 82817-82823

Electrochemical evidence for inclusion complexes of thiotriazinone with cyclodextrins

A. Arvinte, N. Marangoci, A. Nicolescu and M. Pinteala, RSC Adv., 2016, 6, 82817 DOI: 10.1039/C6RA16386F

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