Issue 66, 2016, Issue in Progress
From the journal:

RSC Advances

Surface patterned hydrogel film as a flexible scaffold for 2D and 3D cell co-culture†

Feiyan Zhu,a   Ying Chen,b   Saina Yang,b   Qian Wang,b   Fuxin Liang,*b   Xiaozhong Qu*a  and  Zhongbo Hu*a  

* Corresponding authors

a College of Materials Science and Opto-Electronic Technology, University of Chinese Academy of Sciences, Beijing 100049, China
E-mail: quxz@iccas.ac.cn, huzq@ucas.ac.cn

b State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
E-mail: Liangfuxin@iccas.ac.cn

Abstract

Herein we report a facile route for the preparation of surface patterned dynamic hydrogel films, which are not only a matrix to encapsulate one type of cell in 3D but also a substrate to support aligned aggregates of magnetic silica rods to adhere another type of cell in 2D. This enables the composite hydrogel films to be flexible scaffolds for engineering multi-cellular tissues.

Graphical abstract: Surface patterned hydrogel film as a flexible scaffold for 2D and 3D cell co-culture

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Article information

DOI
https://doi.org/10.1039/C6RA11249H
Article type
Communication
Submitted
01 May 2016
Accepted
17 Jun 2016
First published
21 Jun 2016

RSC Adv., 2016,6, 61185-61189

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Surface patterned hydrogel film as a flexible scaffold for 2D and 3D cell co-culture

F. Zhu, Y. Chen, S. Yang, Q. Wang, F. Liang, X. Qu and Z. Hu, RSC Adv., 2016, 6, 61185 DOI: 10.1039/C6RA11249H

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