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Issue 57, 2016, Issue in Progress
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Iron-catalyzed addition/cyclization cascade of activated alkenes with alcohols: access to carbonyl substituted quinoline-2,4-diones

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Abstract

A convenient and efficient iron-catalyzed radical addition/cyclization cascade of o-cyanoarylacrylamides with alcohols is presented for the synthesis of carbonyl substituted quinoline-2,4(1H,3H)-diones in moderate to excellent yields. This transformation exhibits a wide substrate scope and significant functional group tolerance.

Graphical abstract: Iron-catalyzed addition/cyclization cascade of activated alkenes with alcohols: access to carbonyl substituted quinoline-2,4-diones

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Publication details

The article was received on 07 Apr 2016, accepted on 22 May 2016 and first published on 24 May 2016


Article type: Paper
DOI: 10.1039/C6RA08976C
Citation: RSC Adv., 2016,6, 52391-52394
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    Iron-catalyzed addition/cyclization cascade of activated alkenes with alcohols: access to carbonyl substituted quinoline-2,4-diones

    S. Wang, H. Fu, G. Wang, M. Sun and Y. Li, RSC Adv., 2016, 6, 52391
    DOI: 10.1039/C6RA08976C

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