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Issue 56, 2016, Issue in Progress
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Novel β-galactosynthase–β-mannosynthase dual activity of β-galactosidase from Aspergillus oryzae uncovered using monomer sugar substrates

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Abstract

A novel β-galactosynthase–β-mannosynthase dual-activity of β-galactosidase from Aspergillus oryzae was uncovered, for the first time, using free monosaccharide substrates. The enzyme successfully converted galactose and mannose monomer sugars efficiently into Gal-β(1–6)-Gal and Man-β(1–6)-Man, respectively. The discovery could potentially revolutionize chemoenzymatic glycan and non-digestible oligosaccharide (NDO) syntheses.

Graphical abstract: Novel β-galactosynthase–β-mannosynthase dual activity of β-galactosidase from Aspergillus oryzae uncovered using monomer sugar substrates

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Supplementary files

Article information


Submitted
29 Mar 2016
Accepted
17 May 2016
First published
18 May 2016

RSC Adv., 2016,6, 50833-50836
Article type
Communication

Novel β-galactosynthase–β-mannosynthase dual activity of β-galactosidase from Aspergillus oryzae uncovered using monomer sugar substrates

R. S. Tan, H. Hinou and S.-I. Nishimura, RSC Adv., 2016, 6, 50833
DOI: 10.1039/C6RA08060J

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