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Issue 36, 2016
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Novel micellar form of poplar propolis with high cytotoxic activity

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Abstract

A novel micellar form of propolis based on a biocompatible poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) block copolymer (PEO26PPO40PEO26) is developed. Beneficially, all biologically active lipophilic constituents of propolis are solubilized with the aid of polymeric micelles in aqueous media. The micellar form of the propolis exhibits high in vitro cytotoxicity at relatively low concentrations.

Graphical abstract: Novel micellar form of poplar propolis with high cytotoxic activity

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Article information


Submitted
08 Feb 2016
Accepted
17 Mar 2016
First published
21 Mar 2016

RSC Adv., 2016,6, 30728-30731
Article type
Communication

Novel micellar form of poplar propolis with high cytotoxic activity

P. D. Petrov, C. B. Tsvetanov, P. Mokreva, K. Yoncheva, S. Konstantinov, B. Trusheva, M. Popova and V. Bankova, RSC Adv., 2016, 6, 30728
DOI: 10.1039/C6RA03577A

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