Issue 24, 2016

An improved miniprotein host for fluorogenic supramolecular assembly on the surface of living cells

Abstract

An improved miniprotein host capable of fluorogenic supramolecular assembly with a sI-Pht guest is reported. This improved host, termed 6.2.22, displays significant enhancements in both the EC50 for complexation and fluorescence activation of the sI-Pht guest, allowing for improved resolution of supramolecular complexation on the surface of living yeast.

Graphical abstract: An improved miniprotein host for fluorogenic supramolecular assembly on the surface of living cells

Supplementary files

Article information

Article type
Communication
Submitted
14 Jan 2016
Accepted
10 Feb 2016
First published
11 Feb 2016

RSC Adv., 2016,6, 20381-20385

An improved miniprotein host for fluorogenic supramolecular assembly on the surface of living cells

B. Xu, X. Zhou and C. I. Stains, RSC Adv., 2016, 6, 20381 DOI: 10.1039/C6RA01215A

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