Issue 30, 2016

An aggregation-induced emission-based pH-sensitive fluorescent probe for intracellular acidity sensing

Abstract

A dual-emission pH-sensitive fluorescent probe was developed, which displays green fluorescence in alkaline after deprotonation, while orange emission in acid at aggregated state. This novel probe allows the specific light-on in acidic lysosomes of cancer cells and tumors in nude mice, which indicates its potential application in cancer diagnosis.

Graphical abstract: An aggregation-induced emission-based pH-sensitive fluorescent probe for intracellular acidity sensing

Supplementary files

Article information

Article type
Communication
Submitted
14 Jan 2016
Accepted
29 Feb 2016
First published
02 Mar 2016

RSC Adv., 2016,6, 25416-25419

An aggregation-induced emission-based pH-sensitive fluorescent probe for intracellular acidity sensing

N. Lin, X. Chen, S. Yan, H. Wang, Z. Lu, X. Xia, M. Liang, Y. Wu, L. Zheng, Q. Cao and Z. Ding, RSC Adv., 2016, 6, 25416 DOI: 10.1039/C6RA01167E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements