The UiO-66-SO3H metal–organic framework as a green catalyst for the facile synthesis of dihydro-2-oxypyrrole derivatives

Abstract

The multicomponent domino reaction synthesis of dihydro-2-oxopyrroles has been performed using the sulfonated metal–organic framework, UiO-66-SO₃H (UiO is the University of Oslo), as a highly efficient acid catalyst. The MOF can act as both Brønsted (H⁺) and Lewis acid (Zr⁴⁺) active sites. The protocol presents an environmentally benign as well as a simple experimental and work-up procedure.