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Issue 35, 2016
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Facile, tunable, and SERS-enhanced HEPES gold nanostars

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Abstract

Gold nanoparticles have shown promise as effective tools in biomedicine for drug delivery, imaging, and photo thermal therapy. We present the preparation of gold nanostars (AuNSs) through a two-step approach utilizing a common Good's buffer, HEPES, as a weak reducing agent. AuNSs with tunable branch-lengths up to 30 nm in length were produced in a two-step synthesis. We have investigated the effect of the ionic strength on the AuNS growth and branch length. AuNSs were found to be near-infrared responsive and provide an augmented SERS signal, with an enhancement factor, defined as the magnitude of SERS signal amplification, of approximately 107. The unique branched morphology of the AuNSs confers optical properties advantageous for in vivo biomedical applications.

Graphical abstract: Facile, tunable, and SERS-enhanced HEPES gold nanostars

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Publication details

The article was received on 07 Jan 2016, accepted on 09 Mar 2016 and first published on 16 Mar 2016


Article type: Paper
DOI: 10.1039/C6RA00450D
Citation: RSC Adv., 2016,6, 29669-29673

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    Facile, tunable, and SERS-enhanced HEPES gold nanostars

    S. Saverot, X. Geng, W. Leng, P. J. Vikesland, T. Z. Grove and L. R. Bickford, RSC Adv., 2016, 6, 29669
    DOI: 10.1039/C6RA00450D

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