Base-mediated isocyanide-based three-component reactions: divergent synthesis of spiro-substituted furans and pyrroles†
Abstract
A facile base-mediated isocyanide-based three-component cycloaddition protocol for chemoselective formation of functionalized spiro-substituted furans and pyrroles derivatives has been developed. Fairly good yields of the products, the ready availability of the starting materials and the excellent chemoselectivity are the main advantages of this method.