Issue 3, 2016

Three-component reaction between substituted 2-(2-nitrovinyl)-phenols, acetylenedicarboxylate and amines: diversity-oriented synthesis of novel pyrrolo[3,4-c]coumarins

Abstract

An efficient and straightforward synthetic protocol has been developed for the preparation of pyrrolo[3,4-c]coumarins via FeCl3-promoted three component reaction between substituted 2-(2-nitrovinyl)phenols, acetylenedicarboxylate and amines for the generation of a wide range of structurally interesting and pharmacologically significant compounds.

Graphical abstract: Three-component reaction between substituted 2-(2-nitrovinyl)-phenols, acetylenedicarboxylate and amines: diversity-oriented synthesis of novel pyrrolo[3,4-c]coumarins

Supplementary files

Article information

Article type
Communication
Submitted
06 Nov 2015
Accepted
17 Dec 2015
First published
21 Dec 2015

RSC Adv., 2016,6, 1700-1704

Author version available

Three-component reaction between substituted 2-(2-nitrovinyl)-phenols, acetylenedicarboxylate and amines: diversity-oriented synthesis of novel pyrrolo[3,4-c]coumarins

S. Xue, J. Yao, J. Liu, L. Wang, X. Liu and C. Wang, RSC Adv., 2016, 6, 1700 DOI: 10.1039/C5RA23392E

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