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Issue 45, 2016
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Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding

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Abstract

To provide a molecular insight for guiding polymer coating in surface science and nanotechnology, here we examined the structures of brushed polyethylene glycol(bPEG)- and phosphorylcholine(bPC)-grafted iron oxide nanoparticles and analyzed their protein avoiding properties. We show bPC as an advantageous biomimetic alternative to PEG in rendering stealth nanostructures.

Graphical abstract: Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding

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Article information


Submitted
25 Aug 2016
Accepted
22 Sep 2016
First published
23 Sep 2016

Polym. Chem., 2016,7, 6875-6879
Article type
Communication

Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding

B. Wang, T. Blin, A. Käkinen, X. Ge, E. H. Pilkington, J. F. Quinn, M. R. Whittaker, T. P. Davis, P. C. Ke and F. Ding, Polym. Chem., 2016, 7, 6875
DOI: 10.1039/C6PY01480A

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