“Caged” reagents for miRNA research (siRNA targeting EGFR, involved in miRNA maturation, and mimics of miR-20a, playing a key role in tumor formation and metastasis) were prepared. It was demonstrated that these reagents can be activated by non-toxic to cells red light both in cells and in cell free settings.
A. Meyer, M. Schikora, V. Starkuviene and A. Mokhir, Photochem. Photobiol. Sci., 2016, 15, 1120 DOI: 10.1039/C6PP00046K
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