Jump to main content
Jump to site search

Issue 46, 2016
Previous Article Next Article

A new synthesis and preliminary evaluation of some analogues of mecamylamine – a compound with anti-addiction properties

Author affiliations

Abstract

A new synthesis of mecamylamine – a known anti-hypertensive drug with anti-addictive properties is described. The new route allowed access to two novel analogues whose activity at two nicotinic acetylcholine receptor subtypes was assessed.

Graphical abstract: A new synthesis and preliminary evaluation of some analogues of mecamylamine – a compound with anti-addiction properties

Back to tab navigation

Supplementary files

Publication details

The article was received on 07 Sep 2016, accepted on 25 Oct 2016 and first published on 25 Oct 2016


Article type: Communication
DOI: 10.1039/C6OB01974A
Org. Biomol. Chem., 2016,14, 10787-10798

  •   Request permissions

    A new synthesis and preliminary evaluation of some analogues of mecamylamine – a compound with anti-addiction properties

    D. Mangan, N. McNabola, E. H. Clark, I. Bermudez, S. Wonnacott and J. M. Southern, Org. Biomol. Chem., 2016, 14, 10787
    DOI: 10.1039/C6OB01974A

Search articles by author

Spotlight

Advertisements