Issue 10, 2016

Palladium-catalyzed paraformaldehyde insertion: a three-component synthesis of benzofurans

Abstract

An efficient procedure for 2-aroylbenzofuran preparation from 2-bromophenols, phenacyl bromides and paraformaldehyde is described. The cheap and stable paraformaldehyde served as the carbon source via an in situ formylation reaction.

Graphical abstract: Palladium-catalyzed paraformaldehyde insertion: a three-component synthesis of benzofurans

Supplementary files

Article information

Article type
Communication
Submitted
25 Jan 2016
Accepted
02 Feb 2016
First published
04 Feb 2016

Org. Biomol. Chem., 2016,14, 2819-2823

Palladium-catalyzed paraformaldehyde insertion: a three-component synthesis of benzofurans

X. Cheng, Y. Peng, J. Wu and G. Deng, Org. Biomol. Chem., 2016, 14, 2819 DOI: 10.1039/C6OB00198J

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