Issue 24, 2016

Chiral phosphoric acid catalyzed asymmetric addition of naphthols to para-quinone methides

Abstract

An asymmetric addition of naphthols to in situ generated para-quinone methides catalyzed by a chiral phosphoric acid is described. A range of useful triarylmethanes can be generated from stable general para-hydroxybenzyl alcohols with good efficiency and enantioselectivity.

Graphical abstract: Chiral phosphoric acid catalyzed asymmetric addition of naphthols to para-quinone methides

  • This article is part of the themed collection: New Talent

Supplementary files

Article information

Article type
Paper
Submitted
15 Jan 2016
Accepted
24 Feb 2016
First published
24 Feb 2016

Org. Biomol. Chem., 2016,14, 5751-5754

Chiral phosphoric acid catalyzed asymmetric addition of naphthols to para-quinone methides

Y. F. Wong, Z. Wang and J. Sun, Org. Biomol. Chem., 2016, 14, 5751 DOI: 10.1039/C6OB00125D

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