Flexible synthesis of polyfunctionalised 3-fluoropyrroles†
An efficient and selective approach for the synthesis of polyfunctionalised 3-fluoropyrroles has been developed starting from commercial aldehydes. The methodology is concise, efficient and allows for the modular and systematic assembly of polysubstituted 3-fluoropyrroles. This synthesis provides an alternative and highly convergent strategy for the generation of these chemically and biologically important units.
- This article is part of the themed collection: Contemporary Synthetic Chemistry in Drug Discovery