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Issue 1, 2016
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Electronically modified amine substituted alkynols for regio-selective synthesis of dihydrofuran derivatives

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Abstract

An efficient and simple approach has been developed for the regio-selective synthesis of iodo-substituted dihydrofurans from amine substituted alkynols. The resulting iodo-substituted dihydrofurans have been further diversified by C–C couplings and C–N coupling reactions to afford a diverse range of substituted dihydrofuran derivatives.

Graphical abstract: Electronically modified amine substituted alkynols for regio-selective synthesis of dihydrofuran derivatives

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Supplementary files

Article information


Submitted
30 Sep 2015
Accepted
13 Nov 2015
First published
13 Nov 2015

Org. Biomol. Chem., 2016,14, 288-295
Article type
Paper
Author version available

Electronically modified amine substituted alkynols for regio-selective synthesis of dihydrofuran derivatives

V. V, M. V. Karkhelikar, B. Sridhar, N. Mirzadeh, S. Bhargava and P. R. Likhar, Org. Biomol. Chem., 2016, 14, 288
DOI: 10.1039/C5OB02033F

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