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Issue 26, 2016
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Osmotic pressure-dependent release profiles of payloads from nanocontainers by co-encapsulation of simple salts

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Abstract

The encapsulation of payloads in micro- to nano-scale capsules allows protection of the payload from the surrounding environment and control of its release profile. Herein, we program the release of hydrophilic payloads from nanocontainers by co-encapsulating simple inorganic salts for adjusting the osmotic pressure. The latter either leads to a burst release at high concentrations of co-encapsulated salts or a sustained release at lower concentrations. Osmotic pressure causes swelling of the nanocapsule's shell and therefore sustained release profiles can be adjusted by crosslinking it. The approach presented allows for programing the release of payloads by co-encapsulating inexpensive salts inside nanocontainers without the help of stimuli-responsive materials.

Graphical abstract: Osmotic pressure-dependent release profiles of payloads from nanocontainers by co-encapsulation of simple salts

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Publication details

The article was received on 04 Mar 2016, accepted on 27 May 2016 and first published on 30 May 2016


Article type: Paper
DOI: 10.1039/C6NR01882C
Nanoscale, 2016,8, 12998-13005
  • Open access: Creative Commons BY license
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    Osmotic pressure-dependent release profiles of payloads from nanocontainers by co-encapsulation of simple salts

    S. Behzadi, C. Rosenauer, M. Kappl, K. Mohr, K. Landfester and D. Crespy, Nanoscale, 2016, 8, 12998
    DOI: 10.1039/C6NR01882C

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