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Issue 14, 2016
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Upconversion nanoparticles with a strong acid-resistant capping

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Water-dispersible upconversion nanoparticles (β-NaYF4:Yb3+,Er3+, UCNP) coated with a thin shell of a biocompatible copolymer comprising 2-hydroxyethylmethacrylate (HEMA) and 2-acrylamido-2-methyl-1-propanesulphonsulphonic acid (AMPS), which we will term COP, have been prepared by multidentate grafting. This capping is remarkably resistant to strong acidic conditions as low as pH 2. The additional functionality of the smart UCNP@COP nanosystem has been proved by its association to a well-known photosensitizer (namely, methylene blue, MB). The green-to-red emission ratio of the UC@COP@MB nanohybrid exhibits excellent linear dependence in the 7 to 2 pH range as a consequence of the release of the dye as the pH decreases.

Graphical abstract: Upconversion nanoparticles with a strong acid-resistant capping

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Article information

25 Sep 2015
09 Mar 2016
First published
10 Mar 2016

Nanoscale, 2016,8, 7588-7594
Article type
Author version available

Upconversion nanoparticles with a strong acid-resistant capping

I. Recalde, N. Estebanez, L. Francés-Soriano, M. Liras, M. González-Béjar and J. Pérez-Prieto, Nanoscale, 2016, 8, 7588
DOI: 10.1039/C5NR06653K

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