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Issue 10, 2016
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Comparison of analytical techniques for the identification of bioactive compounds from natural products

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Abstract

Covering: 2000 to 2016

Natural product extracts are a rich source of bioactive compounds. As a result, the screening of natural products for the identification of novel biologically active metabolites has been an essential part of several drug discovery programs. It is estimated that more than 70% of all drugs approved from 1981 and 2006, were either derived from or structurally similar to nature based compounds indicating the necessity for the development of a rapid method for the identification of novel compounds from plant extracts. The screening of biological matrices for the identification of novel modulators is nevertheless still challenging. In this review we discuss current techniques in phytochemical analysis and the identification of biologically active components.

Graphical abstract: Comparison of analytical techniques for the identification of bioactive compounds from natural products

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Publication details

The article was received on 31 Jan 2016 and first published on 01 Jul 2016


Article type: Review Article
DOI: 10.1039/C6NP00016A
Nat. Prod. Rep., 2016,33, 1131-1145

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    Comparison of analytical techniques for the identification of bioactive compounds from natural products

    Ł. Cieśla and R. Moaddel, Nat. Prod. Rep., 2016, 33, 1131
    DOI: 10.1039/C6NP00016A

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