Jump to main content
Jump to site search

Issue 7, 2016
Previous Article Next Article

A complex game of hide and seek: the search for new antifungals

Author affiliations

Abstract

Fungal infections directly affect millions of people each year. In addition to the invasive fungal infections of humans, the plants and animals that comprise our primary food source are also susceptible to diseases caused by these eukaryotic microbes. The need for antifungals, not only for our medical needs, but also for use in agriculture and livestock causes a high demand for novel antimycotics. Herein, we provide an overview of the most commonly used antifungals in medicine and agriculture. We also present a summary of the recent progress (from 2010–2016) in the discovery/development of new agents against fungal strains of medical/agricultural relevance, as well as information related to their biological activity, their mode(s) of action, and their mechanism(s) of resistance.

Graphical abstract: A complex game of hide and seek: the search for new antifungals

Back to tab navigation

Publication details

The article was received on 19 Apr 2016, accepted on 16 May 2016 and first published on 17 May 2016


Article type: Review Article
DOI: 10.1039/C6MD00222F
Med. Chem. Commun., 2016,7, 1285-1306

  •   Request permissions

    A complex game of hide and seek: the search for new antifungals

    H. X. Ngo, S. Garneau-Tsodikova and K. D. Green, Med. Chem. Commun., 2016, 7, 1285
    DOI: 10.1039/C6MD00222F

Search articles by author

Spotlight

Advertisements