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Issue 12, 2016
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Advances in venomics

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Abstract

The term “venomics” was coined to describe the global study of venom and venom glands, targeting comprehensive characterization of the whole toxin profile of a venomous animal by means of proteomics, transcriptomics, genomics and bioinformatics studies. This integrative approach is supported by the rapid evolution of protein, RNA and DNA sequencing techniques, as well as databases, knowledge-bases and biocomputing algorithms. The aim of this review is to illustrate advances in the field of venomics during the last decade, addressing each step of the procedure, from sample collection to data treatment. A special focus is made on new perspectives for a better understanding of the venomous function and for fostering the discovery of new venom-derived drug candidates.

Graphical abstract: Advances in venomics

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Article information


Submitted
08 Jul 2016
Accepted
27 Sep 2016
First published
05 Oct 2016

Mol. BioSyst., 2016,12, 3530-3543
Article type
Review Article

Advances in venomics

V. Oldrati, M. Arrell, A. Violette, F. Perret, X. Sprüngli, J. Wolfender and R. Stöcklin, Mol. BioSyst., 2016, 12, 3530
DOI: 10.1039/C6MB00516K

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